Selank/
Thr-Lys-Pro-Arg-Pro-Gly-Pro · TKPRPGP
Sheet
- Molecular Weight
- 751.86 g/mol
- Molecular Formula
- C₃₃H₅₇N₁₁O₉
- CAS
- 129954-34-3
- Assayed Purity
- ≥ 98.0% (release spec)
- Standard Vial
- Lyophilized
- Source
- Domestic · 3rd-party verified
- Storage
- -20°C lyophilized
Mechanism
Tuftsin-Analog Signaling
BDNF Regulation
Anxiolytic Research
In published research, the synthetic tuftsin analog Selank was shown to regulate brain-derived neurotrophic factor (BDNF) content in the hippocampus and prefrontal cortex of rats (Kolik et al, 2019, PMID 31625062).
In a separate rat study, Selank attenuated aversive signs associated with morphine withdrawal (Konstantinopolsky et al, 2022, PMID 36322304). Selank is a heptapeptide analog of the endogenous immunomodulatory peptide tuftsin.
Citations
- [01]Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats.↗
- [02]Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats.↗
Literature citations verified against PubMed: 2026-07-11.
Questions
In published research, the synthetic tuftsin analog Selank was shown to regulate brain-derived neurotrophic factor (BDNF) content in the hippocampus and prefrontal cortex of rats (Kolik et al, 2019, PMID 31625062). Referenced for mechanism only; for research purposes only.